Granulocytes and Macrophages attack
all microbes equally well, regardless of their nature, by Phagocytosis (from
Greek: Phagein= eat: cytos= cell)
The Inflammatory reaction is a
rapid, local and protective immune response that relies mostly on
phagocytosis. It constitutes the first line of defense against the
aggressor. Since it is identical whatever the aggressor is, it is said to be
non-specific* (Dakroub, 2011).
* Non-Specific: refers to an immune
response that does not depend on the intruder's identity.
In phagocytosis, or 'cell eating' the cell engulfs debris, bacteria,
or other sizable objects. Phagocytosis occurs in specialized cells called
phagocytes, which include macrophages, neutrophils, and other white blood
cells. Invagination produces a vesicle called a phagosome, which usually fuses
with one or more lysosomes containing hydrolytic enzymes. Materials in the
phagosome are broken down by these enzymes and degraded (Pearson
Education, 2012).
Process of Phagocytosis
Image from (Biology / Medicine Animations HD, 2014)
References:
Pearson Education. (2012, February
12). Concept 2 Review: Receptor-Mediated Endocytosis.Retrieved November 30,
2014, from
http://www.phschool.com/science/biology_place/biocoach/biomembrane2/mediated.html.
Biology / Medicine Animations HD.
(2014, March 3). Process of Phagocytosis [HD Animation] [Video
file]. Retrieved from https://www.youtube.com/watch?v=r4-g6tVyUAU.
Dakroub, R. N. (2011). Life and
Earth Sciences (Basic Edition, Grade Eight ed.). Lebanon, Sin El Fil:
Center for Educational Resarch and Development, Educational Company.
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